检验医学与临床2016,Vol.13Issue(24):3443-3445,3.DOI:10.3969/j.issn.1672-9455.2016.24.003
嗜麦芽寡养单胞菌对念珠菌抑制作用观察
Observation of the inhibitory effect of Stenotrophomonas maltophilia on Candida
摘要
Abstract
Objective To explore the inhibitory effect of Stenotrophomonas maltophilia (SMA) upon Candida ,such as Candida albicans(CA) ,candida tropicalis(CT) ,Candida glabrata(CG) ,Candida parapsilosis(CP) ,Candida krusei(CK) etc .Methods Twen‐ty strains of SMA were collected from clinical specimens ,and identified by Gram stain ,Oxygenase test and API 20 NE (French Merieux product) .The inhibitory effect of SMA on Candida was tested by paper method ,cross‐suppression test and co‐culture .Re‐sults The 20 strains of SMA had significant inhibitory effects on Candida ,but did not inhibit the growth of Escherichia coli (ATCC 25922) ,Klebsiella pneumoniae (ATCC 700603) and Pseudomonas aeruginosa (ATCC 27953) .Conclusion SMA has an inhibitory effect on common Candida species ,suggesting that it may be related to the inhibition of fungal hyphae formation by secreting some metabolites .关键词
嗜麦芽寡养单胞菌/念珠菌/抑制作用/十字交叉划线法Key words
Stenotrophomonas maltophilia/Candida/inhibitory effect/cross-streaking method引用本文复制引用
徐令清,王欢,温伟洪,李介华,钟国权,汪峰,侯红艳,孙自镛..嗜麦芽寡养单胞菌对念珠菌抑制作用观察[J].检验医学与临床,2016,13(24):3443-3445,3.基金项目
国家科技重大专项“十二五”资助课题(2012zx10004207-004);广东省清远市科技局产业技术与研究开发专项资金资助项目(2014A005)。 ()