河南科技大学学报（医学版）2016，Vol.34Issue(4)：281-283,3.DOI:10.15926/j.cnki.issn1672-688x.2016.04.013
降钙素原监测在ICU不同病原菌感染中的临床价值
Clinical Value of Serum Procalciton in ICU Patients with Pathogens Infection
佳莉娟 1曹秀琴 2王琦3
作者信息
- 1. 宁夏医科大学基础医学院病原生物学与免疫系，宁夏银川750004
- 2. 解放军534医院内二科，河南洛阳471003
- 3. 宁夏医科大学生育力保持省部级共级教育部重点实验室，宁夏银川750004
- 折叠
摘要
Abstract
Objective To investigate the clinical value of serum procalcitonin ( PCT ) level in ICU patients with different pathogens Infection. Methods 380 cases with infections were selected in ICU from Aug 2013 to Dec 2015 in our hospital. The PCT levels were detected, meanwhile bacteria species were isolated and identified in duration of hospital stay. The clinical value of PCT level were identified for different pathogenic bacteria infection based on the receiver operating characteristic curve ( ROC ) . Results The PCT level with positive rate of G-bacteria was significantly higher than that with fungal and G+bacterial infection(all P<0. 01). However, there was no difference between fungal and G+bacterial infection(P>0 . 05 ) . The PCT level at 2 . 11 ng · mL-1 could distinguish G-bacteria infection from G+bacteria infection with sensitivity 82 . 62% and specificity 80 . 24%, and the area under curve ( AUC ) was 0 . 89 . The PCT level at 5. 08 ng·mL-1 could distinguish G-bacteria infection from fungal infection with sensitivity 68. 16%and specificity 73. 78%, and the AUC was 0. 78. Conclusion PCT level had a high value for identification of G- bacteria with fungal and G+bacteria infection, but low value for fungal and G+ bacteria identification.关键词
感染/降钙素原/重症监护病房/诊断Key words
infection/procalcitonin/intensive careunit/diagnosis分类
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佳莉娟,曹秀琴,王琦..降钙素原监测在ICU不同病原菌感染中的临床价值[J].河南科技大学学报（医学版）,2016,34(4):281-283,3.
