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蒙成药那仁满都拉多糖钙的钙含量及对羟自由基的清除作用研究

乌兰格日乐 张志超 曹楷 师哲 金丽杰

内蒙古民族大学学报(自然科学版)2016,Vol.31Issue(5):385-387,3.
内蒙古民族大学学报(自然科学版)2016,Vol.31Issue(5):385-387,3.DOI:10.14045/j.cnki.15-1220.2016.05.006

蒙成药那仁满都拉多糖钙的钙含量及对羟自由基的清除作用研究

Calcium Content and Scavenging Effects on Hydroxy Radical of Mongolian Medicine Narenmandula Polysaccharide Calcium

乌兰格日乐 1张志超 1曹楷 1师哲 1金丽杰1

作者信息

  • 1. 内蒙古民族大学化学化工学院,内蒙古 通辽 028043
  • 折叠

摘要

Abstract

Using water-extraction and alcohol-precipitation, polysaccharide calcium was prepared by polysaccharide and CaCl2 at 36~37℃, pH=7.3~7.5 under simulated organism conditions. The complexometric titration( micro-titration)——EDTA method was adopted to determine the calci-um content and the colorimetric method was used to measure the scavenging effect on hydroxy radi-cal(·OH). The results showed that the calcium content of polysaccharide calcium was 13.3%, which is much higher than calcium gluconate and has better solubility in water. The concentration of poly-saccharide calcium was 0.125 mg·mL-1~2.0 mg·mL-1, which can scavenge about 53.8%~62.4%of hydroxy radical(·OH). It is concluded that polysaccharide calcium has stronger scavenging effects on hydroxy radical(·OH), but its concentration had no significant effects.

关键词

那仁满都拉/多糖钙/制备/钙含量/羟自由基

Key words

Mongolian medicine Narenmandula/Polysaccharide calcium/Preparation/Calcium content/Hydroxy radical

分类

医药卫生

引用本文复制引用

乌兰格日乐,张志超,曹楷,师哲,金丽杰..蒙成药那仁满都拉多糖钙的钙含量及对羟自由基的清除作用研究[J].内蒙古民族大学学报(自然科学版),2016,31(5):385-387,3.

基金项目

内蒙古自然科学基金项目 ()

通辽市与内蒙古民族大学科技合作项目 ()

内蒙古民族大学学报(自然科学版)

1671-0185

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