中国康复理论与实践2016，Vol.22Issue(12)：1425-1429,5.DOI:10.3969/j.issn.1006-9771.2016.12.013
运动对骨代谢信号通路影响的研究进展
Advance in Exercise for Bone Metabolism Pathways (review)
摘要
Abstract
The process of exercise regulating bone metabolism is complicated, which involves a number of signaling pathways. A large number of studies in vitro have indicated that mechanical stress regulates bone metabolism by Wnt, bone morphogenetic protein (BMP), and osteoprotegerin (OPG)/receptor activator of NF-κB ligand (RANKL)/receptor activator of NF-κB (RANK) signaling pathways. Both the in-tensity and frequency of mechanical stress have varing impact on bone tissue and cells. Plenty of studies in vivo also have shown that exer-cise regulates bone metabolism by key factors in bone metabolism signaling pathways. This paper reviewed the effects of exercise on bone metabolism pathways and their mechanisms.关键词
运动/机械应力/骨代谢信号通路/综述Key words
exercise/mechanical stress/bone metabolism pathway/review分类
医药卫生引用本文复制引用
仝晓阳,张玲莉,郭健民,元宇,邹军..运动对骨代谢信号通路影响的研究进展[J].中国康复理论与实践,2016,22(12):1425-1429,5.基金项目
1.国家自然科学基金项目(No.81572242)；2.上海市人类运动能力开发与保障重点实验室项目(上海体育学院)(No.11DZ2261100)。 （No.81572242）
