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脑梗死患者康复治疗前后血管内皮生长因子水平的比较

卢利萍 桑德春 白帆 陈慧 杨帆 褚宏宇 张晓钰 李欣 刘建华

中国康复理论与实践2016,Vol.22Issue(12):1434-1437,4.
中国康复理论与实践2016,Vol.22Issue(12):1434-1437,4.DOI:10.3969/j.issn.1006-9771.2016.12.015

脑梗死患者康复治疗前后血管内皮生长因子水平的比较

Level of Serum Vascular Endothelial Growth Factor in Patients with Cerebral Infarction before and after Reha-bilitation

卢利萍 1桑德春 2白帆 1陈慧 2杨帆 1褚宏宇 2张晓钰 1李欣 2刘建华1

作者信息

  • 1. 首都医科大学康复医学院,北京市100068
  • 2. 中国康复研究中心北京博爱医院,北京市100068
  • 折叠

摘要

Abstract

Objective To investigate the change of serum vascular endothelial growth factor (VEGF) in cerebral infarction before and af-ter rehabilitation. Methods Forty-eight patients with first cerebral infarction were enrolled from June, 2014 to August, 2016 in Beijing Bo'ai Hospital. Level of serum VEGF was measured by enzyme-linked immunosorbent assay (ELISA) before and six weeks after rehabilitation. The level of serum VEGF of 33 normal subjects was compared with the patients'. Results The level of serum VEGF was higher in the pa-tients group than in the control group before and six weeks after rehabilitation (t>2.540, P<0.05). The level of VEGF was higher in the large area infarction group (>4 cm) than in the small area infarction group (≤4 cm) (t=4.436, P<0.05), and was higher in the short course (less than one month) infarction group than in the long course (more than one month) group (t=2.316, P<0.05). Conclusion VEGF can be main-tained in high level after rehabilitation.

关键词

血管内皮生长因子/脑梗死/康复治疗/血管再生

Key words

vascular endothelial growth factor/cerebral infarction/rehabilitation/vascular regeneration

分类

医药卫生

引用本文复制引用

卢利萍,桑德春,白帆,陈慧,杨帆,褚宏宇,张晓钰,李欣,刘建华..脑梗死患者康复治疗前后血管内皮生长因子水平的比较[J].中国康复理论与实践,2016,22(12):1434-1437,4.

基金项目

中央级公益性科研院所基本科研业务费专项资金(No.2014CZ-35)。 (No.2014CZ-35)

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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