中国内镜杂志2016，Vol.22Issue(12)：90-93,4.DOI:10.3969/j.issn.1007-1989.2016.12.019
内镜黏膜下剥离术治疗胃肠道神经内分泌肿瘤的临床观察
Endoscopic submucosal dissection in treatment of gastrointestinal neuroendocrine neoplasms
庄惠军 1李秀梅 1潘丽云 1李世群 1沈许德 1陈进忠 1姚礼庆 1苏虹 1雷天霞 1杨炜琳 1吴建海 1郑永胜1
作者信息
- 1. 厦门大学附属第一医院 内镜中心，福建 厦门 361003
- 折叠
摘要
Abstract
Objective To investigate the feasibility and efifcacy of endoscopic submucosal dissection (ESD) for gastrointestinal neuroendocrine neoplasms (GI-NENs).Methods 52 patients with conifrmed histological diagnosis of GI-NENs performed ESD from January 2011 to December 2015 were included. The endoscopic morphology of tumor was summarized. Complete resection rate, complications, clinicopathological characteristics, and follow-up results were evaluated.Results There were 16 cases of stomach, 9 cases of colon and rectum 27 cases. Most of the lesions were submucosal uplift. A few of lesions looked like polyps. All the lesions were one-time whole diseased. 44 lesions were NET-G1, 8 lesions were NET-G2. Complete resection rate was 94.23%. 2 cases of rectal lesions infringemented intrinsic muscle layer, and got additional surgery. 1 case of rectal perforation, which was managed by endoscopic treatment and conservative treatment. All cases did not appear haemorrhage. During a mean follow-up period of 22.6 months, local recurrences occurred in 1 case of stomach, and treated with second line ESD. No cases lymph node and distant metastasis were found.Conclusion ESD appears to be a feasible, safe and effective treatment for GI-NENs with strict endoscopic treatment indications.关键词
内镜黏膜下剥离术/神经内分泌肿瘤/胃肠Key words
endoscopic submucosal dissection (ESD)/neuroendocrine neoplasms (NENs)/gastrointestinal分类
医药卫生引用本文复制引用
庄惠军,李秀梅,潘丽云,李世群,沈许德,陈进忠,姚礼庆,苏虹,雷天霞,杨炜琳,吴建海,郑永胜..内镜黏膜下剥离术治疗胃肠道神经内分泌肿瘤的临床观察[J].中国内镜杂志,2016,22(12):90-93,4.
