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长期食用何首乌对小鼠造血系统的影响

石桂英 白琳

中国比较医学杂志2016,Vol.26Issue(12):10-13,4.
中国比较医学杂志2016,Vol.26Issue(12):10-13,4.DOI:10.3969/j.issn.1671-7856.2016.12.003

长期食用何首乌对小鼠造血系统的影响

Effects of long-term consumption of Fallopia multiflora on mouse hematopoietic system

石桂英 1白琳1

作者信息

  • 1. 中国医学科学院北京协和医学院实验动物研究所,卫生部人类疾病比较医学重点实验室,北京 100021
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摘要

Abstract

Objective To investigate the effects of long-term consumption of Fallopia multiflora on mouse hematopoietic system.Methods Forty 10-month old female C57BL/6J mice were equally divided into two groups at random, the control group fed with normal food , and the experimental group , given food with added Fallopia multiflora. After 10 month, the mice were sacrificed, and the peripheral blood, spleen, thymus and bone marrow cells were examined by flow cytometry.Results In the mice fed with Fallopia multiflora, the percentage of B cells in the spleen and CD 4 +cells in the thymus were increased , and CD8 + cells in the thymus and bone marrow hematopoietic stem cells were decreased , among the bone marrow cells , G0 cells were increased , but G1 and G2/S/M cells decreased .Conclusions Long-term proper consumption of Fallopia multiflora can delay the ageing of the hematopoietic system , and sustain its stability.

关键词

何首乌/流式细胞术/造血系统

Key words

Fallopia multiflora/Flow cytometer/hematopoietic system/Bone marrow/Thymus/Mice

分类

医药卫生

引用本文复制引用

石桂英,白琳..长期食用何首乌对小鼠造血系统的影响[J].中国比较医学杂志,2016,26(12):10-13,4.

基金项目

国家自然科学基金青年科学基金项目(No.81200256);北京市自然基金项目(No7132161)。 ()

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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