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大鼠清醒状态下尾静脉注射的快速操作技巧与体会

张阔 洪寿海 何芹芹 马思宇 王凝露 李强 王慎军 赵雪 郭义

中国比较医学杂志2016,Vol.26Issue(12):81-84,4.
中国比较医学杂志2016,Vol.26Issue(12):81-84,4.DOI:10.3969/j.issn.1671-7856.2016.12.016

大鼠清醒状态下尾静脉注射的快速操作技巧与体会

A quick operating technique and experience of tail vein injection in conscious rats

张阔 1洪寿海 2何芹芹 1马思宇 1王凝露 1李强 3王慎军 1赵雪 1郭义1

作者信息

  • 1. 天津中医药大学实验针灸学研究中心,天津 300193
  • 2. 浙江省中医院,浙江 310006
  • 3. 湖南中医药高等专科学校,湖南 412012
  • 折叠

摘要

Abstract

Objective To introduce the operation skills of tail vein injection in conscious rats , and improve the success rate of ingection .Methods The rat was fixed by the operator with a self-made binding clothes , one person assists to fix the rat tail, one person performs puncture , and one person performs injection .During the injection process , we should minimize the injury to the rat tail and the stress caused by operation , strictly limit the needle point , the number of puncture , the maximum dose and injection speed , and to make the needle position away from the injection site to avoid contamination and waste of the drug solution .Results The operation method was successfully established and it was fast , stable, with good repeatability and high degree of coordination .Conclusion This operation is rapid, reliable and stable, worthy of recommendation , especially for the intravenous injection of expensive drugs .

关键词

清醒/大鼠/尾静脉注射

Key words

Conscious rat/Tail vein injection

分类

医药卫生

引用本文复制引用

张阔,洪寿海,何芹芹,马思宇,王凝露,李强,王慎军,赵雪,郭义..大鼠清醒状态下尾静脉注射的快速操作技巧与体会[J].中国比较医学杂志,2016,26(12):81-84,4.

基金项目

国家自然科学基金重点项目资助(编号81330088);国家自然科学基金资助项目资助(81303025)。 ()

中国比较医学杂志

OA北大核心CSTPCD

1671-7856

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