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环境中细菌抗药性的研究进展

朱阵 李冰 周绪正 魏小娟 程富胜 张继瑜

中国畜牧兽医2016,Vol.43Issue(12):3368-3409,42.
中国畜牧兽医2016,Vol.43Issue(12):3368-3409,42.DOI:10.16431/j.cnki.1671-7236.2016.12.042

环境中细菌抗药性的研究进展

Research Progress on Bacterial Resistance in Environment

朱阵 1李冰 1周绪正 1魏小娟 1程富胜 1张继瑜1

作者信息

  • 1. 中国农业科学院兰州畜牧与兽药研究所,农业部兽用药物创制重点实验室,兰州 730050
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摘要

Abstract

Antibiotic resistance genes have become a recognized environmental pollutant,threat-ening the ecological safety and human health.The application of antibiotics in the clinical and ani-mals breeding,making the environmental microorganisms living with the impact of the residue of antibiotics and elements of resistance genetic and leading to antibiotic resistant bacteria to gain a competitive advantage and destroyed the stability of ecosystem.In this paper,we expounded the concept of resistance gene transmission by the view of macro environment.Through analyzing the mechanism of resistance development,environmental pollution caused by drug resistance and the impact of environmental microorganism for drug resistance,we clarified the key role of the envi-ronment in the development of the characteristics of bacterial resistance and analysis environmen-tal resistance.Such as the ecological diversity of flora,the types and the spread of resistant bacte-ria,the residues of antibiotics and the transmission of the resistance genes.

关键词

抗生素/抗性基因/环境微生物

Key words

antibiotic/resistance genes/environmental microorganisms

分类

农业科技

引用本文复制引用

朱阵,李冰,周绪正,魏小娟,程富胜,张继瑜..环境中细菌抗药性的研究进展[J].中国畜牧兽医,2016,43(12):3368-3409,42.

基金项目

国家自然科学基金(31272603、31101836) (31272603、31101836)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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