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高压氧治疗成人出血型烟雾病的疗效分析和风险评估

王霞 戴嵬

中国卒中杂志2016,Vol.11Issue(12):1019-1022,4.
中国卒中杂志2016,Vol.11Issue(12):1019-1022,4.DOI:10.3969/j.issn.1673-5765.2016.12.005

高压氧治疗成人出血型烟雾病的疗效分析和风险评估

Effect Analysis and Risk Evaluation of Hyperbaric Oxygen Therapy on Hemorrhagic Moyamoya Disease in Adult

王霞 1戴嵬2

作者信息

  • 1. 210007 南京中华医学会高压氧分会脑复苏研究中心,南京紫金医院神经内科
  • 2. 全军神经外科研究所,南京军区南京总医院神经外科脑血管病治疗中心
  • 折叠

摘要

Abstract

Objective To investigate the effect of hyperbaric oxygenation therapy (HBOT) after hemorrhagic-type Moyamoya disease (hMMD) in adult and treatment-related risk factors. Methods A total of 41 adult patients with hMMD admitted from 2010 to 2015 were prospectively studied. The patients were divided into HBOT group (21 cases) and control group (20 cases). Modiifed Rankin Scale (mRS) of neurologic assessments were performed on the 90th day after onset. The effects and related risks of two groups were compared. Logistic regression analysis was used to analyze the risk factors of treatment effect. Results mRS of the 90th day after onset in the HBOT group was lower than the control group (P=0.003). The multivariate Logistic regression analysis showed that the risk factor associated with treatment effect in the HBOT group was frequency of HBOT (OR 0.790, 95%CI0.681-0.903,P=0.001). Conclusion HBOT is effective and safe after Moyamoya disease. Frequency of HBOT is the factor to inlfuence on the treatment effect.

关键词

高压氧/成人/出血型烟雾病

Key words

Hyperbaric oxygenation/Adult/Hemorrhagic Moyamoya disease

引用本文复制引用

王霞,戴嵬..高压氧治疗成人出血型烟雾病的疗效分析和风险评估[J].中国卒中杂志,2016,11(12):1019-1022,4.

中国卒中杂志

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1673-5765

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