北京中医药大学学报2016，Vol.39Issue(12)：1048-1053,6.DOI:10.3969/j.issn.1006-2157.2016.12.014
颊针对类风湿关节炎家兔镇痛效应特性的研究
Relationship of time and analgesic effect of buccal acupuncture on rabbits with rheumatoid arthritis
摘要
Abstract
Objective To explore the relationship of time and analgesic effect of buccal acupuncture on rabbits with rheumatoid arthritis (RA),so as to provide the experimental basis for the clinical practice of buccal acupuncture.Methods Altogether 40 rabbits were randomly divided into normal group,model group,body acupuncture group and buccal acupuncture group (each n =10).RA model was induced by subcutaneous injection of ovalbumin.After modeling,rabbits of body acupuncture group were needled at the acupoint of bilateral “Xiyan”and “Tsusanli”and those of buccal acupuncture group were needled at the buccal acupoint of “knee”once daily for ten times.Heat pain threshold at the time point of 0,5, 15,30,60,120,and 240 minutes were recorded at the 1 st ,4th ,7 th ,and 10th treatment.Results The buccal acupuncture and body acupuncture both showed definite analgesia effect.The heat pain threshold of buccal acupuncture group began to increase after five-minute treatment,reached the peak value at the 30th minute,then declined at the 60th minute to the same as that before treatment at the 240th minute.The variation trend of heat pain threshold of body acupuncture group was in common with that of buccal acu-puncture group,but the pain threshold at the 240th minute was higher than that before treatment.Con-clusion Buccal acupuncture against pain showed obvious effect-time relationship which was as similar as that of body acupuncture,but the onset time of buccal acupuncture was shorter than that of body acu-puncture,and the duration was shorter.Furthermore,the analgesic effect of buccal acupuncture showed no relationship with times.关键词
颊针/镇痛效应/时效曲线/家兔Key words
buccal acupuncture/analgesic effect/time-effect relationship of acupuncture/rabbits分类
医药卫生引用本文复制引用
蒲瑞生,方晓丽,杜小正,颉旺军,秦晓光,苏成红..颊针对类风湿关节炎家兔镇痛效应特性的研究[J].北京中医药大学学报,2016,39(12):1048-1053,6.基金项目
国家自然科学基金项目 （）
