重庆医学2016，Vol.45Issue(36)：5063-5065,5068,4.DOI:10.3969/j.issn.1671-8348.2016.36.007
食管活瓣成形-胃食管套接术预防食管癌术后吻合口并发症的效果分析
Esophageal valve forming esophageal and gastric sleeve joint surgery for preventing postoperative anastomotic complications of esophageal cancer
摘要
Abstract
Objective To clarify the effect of esophageal valve forming esophageal and gastric sleeve joint surgery for preven‐ting postoperative anastomotic complications of esophageal cancer .Methods A randomized controlled trial was designed to incorpo‐rate a total of 394 patients with esophageal cancer from January 2010 to June 2013 .This study has been registered in the Chinese clinical trial center and received a registration number :ChiCTR‐TRC‐13003817 .Among them ,9 cases (2 .3% ) were excluded be‐cause of the non line esophageal cancer radical operation .The remaining patients were randomly divided into two groups ,191 cases in group A and 194 cases in group B ,according to the principle of random grouping .Group A was experimental group ,patients ac‐cepted esophageal valve forming esophageal and gastric sleeve joint surgery ,and group B was the control group ,patients received conventional anastomosis .Results The incidence of anastomotic leakage after operation in group A and group B were 4 .1% and 3 .6% ,thse results were not statistically significant (P=0 .768) .In the observation of anastomotic stenosis ,7 patients died after sur‐gery .In the remaining cases ,there were 13 cases (6 .9% ) and 25 cases (13 .2% ) in group A and group B ,respectively ,the differ‐ence was statistically significant (P=0 .044) .Furthermore ,reflux oesophagitis and Barrett′s epithelium were found in 105 patients (55 .3% ) in group B ,and 54 (28 .7% ) patients in group A ,the difference was statistically significant (P<0 .01) .Conclusion E‐sophageal valve forming esophageal and gastric sleeve joint surgery can effectively prevent postoperative gastroesophageal reflux , but also can reduce the postoperative incidence of anastomotic stenosis .关键词
胃食管吻合/食管肿瘤/吻合口瘘/吻合口狭窄Key words
esophagectomy/esophageal neoplasms/anastomotic leakage/anastomotic stricture分类
医药卫生引用本文复制引用
刘权兴,冯勃翔,侯兵,陈伟,李静孟,崔珂钒,戴纪刚..食管活瓣成形-胃食管套接术预防食管癌术后吻合口并发症的效果分析[J].重庆医学,2016,45(36):5063-5065,5068,4.基金项目
国家自然科学基金资助项目（81172238）；第三军医大学临床科研基金（2014YLC24）。 （）
