湖南中医药大学学报2016,Vol.36Issue(12):37-41,5.DOI:10.3969/j.issn.1674-070X.2016.12.010
中药滋肾养膜方对宫腔粘连内膜修复的临床研究
Clinical Study of Zishen Yangmo Decoction on Repairing Endometrium of Intrauterine Adhesions
摘要
Abstract
Objective To observe the clinical effects of TCM Zishen Yangmo Decoction combined with hysteroscopy technology on repairing endometrium of patients with intrauterine adhesions, and investigate the clinical effect of TCM on treatment of intrauterine adhesions. Methods Clinical medical records of 100 patients with intrauterine adhesions from Profes-sor You Zhaoling's Obstetrics and Gynecology Studio and Department Of Gynaecology of the First Hospital of Changsha were collected and observed. The patients were randomly divided into two groups, 50 cases in control group were treated with hysteroscopy technology and Western medicine (female progestogen sequential therapy), 50 cases in experimental group were given with Zishen Yangmo Decoction on the basis of the control group, for 3 consecutive periods of treatment. The re-covery of menstrual quantity, the improvement of TCM symptoms and effects on the lining of the uterus of patients were ob-served. Results The age, course of the disease, uterine cavity operation times, abortion times and TCM symptoms in experi-mental group and control group were compared with that before treatment, there was no obvious difference, the result showed homogeneous comparability. (2) The total effective rate of comprehensive effect was 88% in experimental group after treatment, which was higher than that of control group (84%), the differences between two groups were analyzed by Radit, there was no statistical significance. (3) The clinical symptoms improved obviously in two groups after treatment, with statisti-cal significance (P<0.05). (4) The experimental group showed better than control group in improving premenstrual breast bilges, fatigue, insomnia, forgetfulness of god and sallow or dull complexion after comparing the changes of main symptoms in two groups after treatment, there was obvious difference (P<0.05), the other symptoms and signs in the two groups were not statistically significant (P>0.05). (5)After treatment, the cycle, period, quantity, color and quality of menstruation were obviously improved. (6) The endometrial thickness after treatment was thicker than that before by comparing the two groups, with statis-tical significance (P<0.05), while the degree of thickening in experimental group was more larger than that in control group, but there was no statistically significance (P>0.05). Conclusion Zishen Yangmo Decoction combined with hysteroscopy technol-ogy and Western medicine treatment show good effects on repairing endometrium of patients with intrauterine adhesions, with exact clinical curative effect. They could obviously increase the patient's menstrual quantity and improve TCM clinical symp-toms, which is worthy of popularization.关键词
宫腔粘连/滋肾养膜方/宫腔粘连分离术/雌孕激素序贯疗法Key words
intrauterine adhesion/Zishen Yangmo decoction/intrauterine adhesions separation technique/female progestogen sequential therapy分类
医药卫生引用本文复制引用
刘丽文,杨超兰,尤昭玲..中药滋肾养膜方对宫腔粘连内膜修复的临床研究[J].湖南中医药大学学报,2016,36(12):37-41,5.基金项目
长沙市科技局2015年指导性科技计划项目(k15ZD023-33)。 ()