临床误诊误治2016，Vol.29Issue(12)：45-48,4.DOI:10.3969/j.issn.1002-3429.2016.12.018
恶性外周神经鞘瘤误诊为糖尿病足二例报告
Malignant Peripheral Nerve Sheath Tumor Misdiagnosed as Diabetic Foot:a Report of 2 Cases
王璐宁 1杨彩哲 1吴石白1
作者信息
- 1. 100142 北京，解放军空军总医院内分泌科
- 折叠
摘要
Abstract
Objective To improve understanding of clinicians about malignant peripheral nerve sheath tumor ( MPNST) in order to reduce misdiagnosis and mistreatment. Methods Clinical data of 2 MPNST patients misdiagnosed as having diabetic foot was retrospectively analyzed, and related literature was reviewed. Results The 2 patients were admitted for foot ulcerate and elevated level of blood sugar. The 2 patients were treated as soft-tissue infection of foot skin and paronych-ia with poor effectiveness in other hospitals, and elevated level of blood sugar were found, but protracted course of disease in wound surface was found after hypoglycemic therapy. Medical examinations such as vascular ultrasound for lower extremity, electromyogram and electrocardiogram showed that no obviously lesions of diabetic peripheral vasculopathy and nerves, and blood-glucose level was controlled well. The histopathological examination for wound surface tissues showed S-100( +), and then MPNST was confirmed. One patient refused further treatment and discharged with losing follow-up; no abnormal was found in another patient by ultrasound for surface lymph nodes, abdomen and pelvic cavity, cranial computed tomography and total body of bone scanning, and toe amputation was performed, and then the patient was discharged after wound healing. No indisposition was told during 1 year of follow-up. Conclusion MPNST in foot is rare, and therefore clinicians should improve awareness and take histopathologic examinations as early as possible to confirm diagnosis and treatment so as to avoid or de-crease misdiagnosis and mistreatment.关键词
神经鞘肿瘤/误诊/糖尿病足Key words
Nerve sheath neoplasms/Misdiagnosis/Diabetic foot分类
医药卫生引用本文复制引用
王璐宁,杨彩哲,吴石白..恶性外周神经鞘瘤误诊为糖尿病足二例报告[J].临床误诊误治,2016,29(12):45-48,4.
