摘要
Abstract
Objective: In the treatment of malignant tumors, the quality of life (QOL) of patients has attracted increasing attention. In this study, postoperative clinical outcomes of patients with esophageal cancer were collected and questionnaire survey was carried out to explore factors that influence the QOL. Methods:From September 2007 to May 2011, 224 patients with esophageal cancer undergone esophageal resection in our hospital were divided into 4 groups according to the surgical approaches: group A (open surgery + gastric tube, 52 cases), group B (open surgery + whole stomach, 52 cases), group C (minimally invasive surgery + gastric tube, 60 cases) and group D (minimally invasive surgery + total gastrectomy group, 60 cases). Postoperative clinical outcomes were collected. The questionnaire was developed according to QLQ-C30 questionnaire and esophageal cancer-specific questionnaire QLQ-OES24, and administrated during the follow-up in the 3 rd week, 6 th and 12 th month after surgery to evaluate the QOL. Results: The age, preoperative pulmonary function, preoperative feeding, location of lesions, tumor stage and pathological types among different groups showed no significant difference. The operation time and blood loss in groups C and D were less than those of group A and B(P<0.05). Three weeks after surgery, the QOL of groups C and D were better than that of groups A and B (P<0.05). Six months after surgery, the QOL had improved, and the QOL of group C and D was superior to that of groups A and B (P<0.05), and the QOL of group A was better than that of group B (P< 0.05). Twelve months after surgery, the QOL was further improved, the QOL of groups A and became better than that of groups B and D(P < 0.05), but the comparison between groups A and C, or between groups B and D showed no statistically significant different. Conclusion: The minimally invasive surgery contributes to the improvement of QOL during early postoperative period (3 weeks to 6 months) in the patients with esophageal cancer, while gastric tube exhibited gradually increasing benefits in long term.关键词
食管癌/微创外科/管胃/生活质量Key words
Esophageal cancer/Minimally invasive surgery/Gastric tube/Quality of life分类
临床医学
