世界中医药2016，Vol.11Issue(11)：2367-2369,2374,4.DOI:10.3969/j.issn.1673-7202.2016.11.043
二补助育汤对胚泡着床障碍小鼠子宫内膜容受性的影响
Effect of Erbu Zhuyu Decoction on Endometrium Receptivity of Rats Model with Embryo Implantation Dysfunction
摘要
Abstract
Objective:To investigate the effects of Erbuzhuyu Decoction on endometrium receptivity of rats model with embryo im -plantation dysfunction .Methods:Rats model with embryo implantation dysfunction was prepared for the study on expression chan -ges of endometrial SCFmRNA , HOXA-10 mRNA, LIF, ER, PR andανβ3.Results:GnRHa+, HMG+, HCG scheme may re-duce the endometrium receptivity , and Erbu Zhuyu Decoction may regulate regulate the expression of relevant regulating factors in networks of rat endometrial microenvironment to improve endometrium receptivity .Conclusion:Erbu Zhuyu Decoction is bound to have the effect on endometrium receptivity and its activity pathway is multi-targeted and multi-linked.关键词
二补助育汤/体外授精-胚胎移植/子宫内膜容受性/干细胞因子/同源盒基因Key words
Erbuzhuyu Decoction/IVF-ET/Endometrium receptivity/SCF/HOXA-10分类
医药卫生引用本文复制引用
江媚,刘雁峰,王铁枫,石玥..二补助育汤对胚泡着床障碍小鼠子宫内膜容受性的影响[J].世界中医药,2016,11(11):2367-2369,2374,4.基金项目
2012国家自然科学基金项目（编号81273789）---二补助育汤调节子宫内膜容受性的效应机制及其与 SCFmRNA 表达相关性研究；2014国家自然科学基金项目（编号81473721）---基于NK／M-CSF／NO通路的二补助育汤调节子宫内膜容受性效应机制相关性研究 （）
