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依托咪酯不同给药时机和速率在无痛胃镜检查中对肌阵挛发生的影响

金亮 罗方毅 徐丹 张明敏 鲁恒

中国保健营养2016,Vol.26Issue(30):33-33,34,2.
中国保健营养2016,Vol.26Issue(30):33-33,34,2.

依托咪酯不同给药时机和速率在无痛胃镜检查中对肌阵挛发生的影响

The effects of different timing and injection speed of etomidate on myoclonus occurance in painless gastroscopy

金亮 1罗方毅 1徐丹 1张明敏 1鲁恒1

作者信息

  • 1. 乐山市人民医院麻醉科,四川 乐山 614000
  • 折叠

摘要

Abstract

Objective The ef ects of dif erent timing and injection speed of etomidate on myoclonus occurance in painless gastroscopy.Methods 218 painless gastroscopy patients are di-vided into 4 groups ramdomly according to dif erent timing and rate of intravenous injection of etomidate after giving midazolam and sufentanil.Group 1:1 mintute after giving midazolam and sufentanil,intravenous inject etomidate 0.2mg/kg(51 cases)in 10 seconds;Group 2,1 mintute after giving midazolam and sufentanil,intravenous inject etomidate 0.2mg/kg(56cases)in 30 seconds;Group 3,2 mintutes after giving midazolam and sufentanil,intravenous inject etomidate 0.2mg/kg(53cases)in 10 seconds;Group 4,2 mintutes after giving midazolam and sufentanil, intravenous inject etomidate 0.2mg/kg(58cases)in 30 seconds.After intravenous injecting etomidate,observe and record 2min myoclonus positive rate and occurrence classification.Results Myoclonus positive rates of four groups were 82.4%,35.7%,17% and 6.9%.Compared with group 1,myoclonus positive rate and occurrence classification in group 2,3and4,significantly re-duced;compared with group 2,nausea and vomiting,myoclonus positive rate and occurrence classification in group 3 and 4 significantly reduced;compared with group 3,myoclonus positive rate and occurrence classification in group 4 significantly reduced.Conclusion 2 mintutes after giving midazolam and sufentanil,intravenous injection of etomidate can significantly reduce myoclo-nus positive rate and occurrence classification,slow injection of etomidate can significantly reduce myoclonus positive rate and occurrence classification.

关键词

依托咪酯/给药时机/给药速率/肌阵挛/无痛胃镜

Key words

Etomidate/Injection timing/Injection speed/Painless gastroscopy

分类

医药卫生

引用本文复制引用

金亮,罗方毅,徐丹,张明敏,鲁恒..依托咪酯不同给药时机和速率在无痛胃镜检查中对肌阵挛发生的影响[J].中国保健营养,2016,26(30):33-33,34,2.

中国保健营养

1004-7484

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