中国感染控制杂志2016，Vol.15Issue(12)：952-955,4.DOI:10.3969/j.issn.1671-9638.2016.12.014
西安市结核分枝杆菌耐药基线调查
Baseline survey on drug resistance of Mycobacterium tuberculosis in Xi’an city
摘要
Abstract
Objective To investigate the baseline condition of initial and acquired drug resistance in patients with pulmonary tuberculosis in Xi’an city,and provide a scientific basis for the prevention and control of drug-resistant tuberculosis.Methods Patients with positive Mycobacteriumtuberculosis(MT)culture and received initial treatment and re-treatment in tuberculosis clinics of 14 districts (counties)in Xi’an and Xi’an Chest Hospital in 2015 were in-cluded in the study,antimicrobial susceptibility testing of 4 kinds of first-line anti-tuberculosis drugs were per-formed.Results The overall drug resistance rate of MT in Xi’an city was 31 .9% ,multidrug resistance rate (MDR) was 7.0% . Drug resistance rate and MDR in initial treatment group were 27.3% and 3.5% respectively,in re-treatment group were 59.5% and 28.6% respectively,drug resistance rate and MDR in re-treatment group were both higher than initial treatment group (both P<0.001).Conclusion The overall drug resistance rate of pulmona-ry tuberculosis patients in Xi’an city is lower than the whole nation,but MDR is slightly higher than the national level,although TB prevention and control work has achieved some success,the situation is still serious,the man-agement of patients with initial treatment should be strengthened to reduce the occurrence of drug resistance.关键词
结核分枝杆菌/肺结核/抗结核药物/耐药/耐多药/基线调查Key words
Mycobacterium tuberculosis/pulmonary tuberculosis/anti-tuberculosis drug/drug resistance/multi-drug resistance/baseline survey分类
医药卫生引用本文复制引用
李于于,曾令城,柳巍..西安市结核分枝杆菌耐药基线调查[J].中国感染控制杂志,2016,15(12):952-955,4.基金项目
西安市科技局项目［SF1208（5）］ （）
