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鼻息肉组织核因子-κB和白细胞介素4的表达及意义

万贝贝 胡乐农 徐红伟

中国现代医学杂志2016,Vol.26Issue(24):43-46,4.
中国现代医学杂志2016,Vol.26Issue(24):43-46,4.DOI:10.3969/j.issn.1005-8982.2016.24.009

鼻息肉组织核因子-κB和白细胞介素4的表达及意义

Expression and significance of NF-κB/IL-4 gene in nasal polyp

万贝贝 1胡乐农 1徐红伟1

作者信息

  • 1. 浙江省丽水市中心医院,浙江 丽水 323000
  • 折叠

摘要

Abstract

Objective To investigate the different expression of nuclear factor -κb and lnterleukin 4 (IL-4) gene in tissue of the nasal polyp. Methods A number of 90 cases of nasal polyp were collected as experimental group and 80 cases inferior turbinate tissues as normal group. Real-time quantitative reverse transcriptase polymerase chain reaction (RT-PCR) method was used to detect the different expression of NF-κB and IL-4 gene, and relative analysis was used to analyzed the results. Results Compared with normal group, the expression of NF-κB and IL-4 gene in expermental group was significantly increased ( < 0.05). Conclusions The expressions of NF-κB and IL-4 are increased in experimental group, which may relate with the occurrence and development of nasal ployp.

关键词

核因子- κB/白细胞介素4/鼻息肉

Key words

NF-κB/IL-4/nasal polyp

分类

医药卫生

引用本文复制引用

万贝贝,胡乐农,徐红伟..鼻息肉组织核因子-κB和白细胞介素4的表达及意义[J].中国现代医学杂志,2016,26(24):43-46,4.

中国现代医学杂志

OA北大核心CSTPCD

1005-8982

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