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MIC-1、G17及PG1对胃癌诊断价值及感染病原菌的影响研究

陆兴热 陈凤羽 杨德兴 刘孝文 袁雕 资云菊 何祥 和润泞

中国现代医学杂志2016,Vol.26Issue(24):47-50,4.
中国现代医学杂志2016,Vol.26Issue(24):47-50,4.DOI:10.3969/j.issn.1005-8982.2016.24.010

MIC-1、G17及PG1对胃癌诊断价值及感染病原菌的影响研究

Value of MIC-1 and G17/PG1 in diagnosis of gastric cancer and variation after pathogen infection

陆兴热 1陈凤羽 1杨德兴 2刘孝文 1袁雕 1资云菊 1何祥 1和润泞1

作者信息

  • 1. 云南省文山壮族苗族自治州人民医院检验科,云南 文山 663000
  • 2. 云南省文山壮族苗族自治州人民医院病理科,云南 文山 663000
  • 折叠

摘要

Abstract

Objective To investigate the value of MIC-1 and G17, PG1 in the diagnosis of gastric cancer and the expression variation after pathogen infection. Methods From April 2010 to August 2015, 120 cases of early gastric cancer and 140 cases of gastric cancer in the hospital were analyzed. The serum MIC-1 and G17, PG1 concentration were assayed by ELISA method. The serum MIC-1 and G17, PG1 were detected in infected patients after operation. At the same period, 120 healthy subjects and 110 un-infected patients in our department were taken as control. Results The serum MIC-1 and G17, PG1 were increased greatly ( <0.05) in gastric cancer patients compared with control. These parameters were also up-regulated ( < 0.05) after infection. The result also showed that serum interleukins, including IL-1, IL-2, IL-3, IL-6 and IL-10 had similar changes with MIC-1. Conclusions MIC-1 and G17, PG1 are potential indicators in the diagnosis of gastric cancer and can be increased after infection.

关键词

胃癌/胃泌素/胃蛋白酶原/人巨噬细胞抑制因子-1

Key words

gastric cancer/G17/PG1/MIC-1

分类

医药卫生

引用本文复制引用

陆兴热,陈凤羽,杨德兴,刘孝文,袁雕,资云菊,何祥,和润泞..MIC-1、G17及PG1对胃癌诊断价值及感染病原菌的影响研究[J].中国现代医学杂志,2016,26(24):47-50,4.

基金项目

2013年文山州科技计划专项项目经费资助项目 ()

中国现代医学杂志

OA北大核心CSTPCD

1005-8982

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