中国现代医学杂志2016，Vol.26Issue(24)：51-53,3.DOI:10.3969/j.issn.1005-8982.2016.24.011
急性心力衰竭患者联合检测血清糖类抗原CA125和N末端脑钠肽原的临床意义
Prognostic value of carbohydrate antigen-125 and N-terminal pro-brain natriuretic peptide levels in patients with acute heart failure
汤子鸣 1秦俭2
作者信息
- 1. 北京大学国际医院，北京 102206
- 2. 首都医科大学宣武医院，北京 100053
- 折叠
摘要
Abstract
Objective To evaluate the prognostic value of serum carbohydrate antigen-125 (CA125) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with acute heart failure. Methods Sixty-eight patients with acute left heart failure were included and divided into three groups according to different prognosis six months after discharge:dead (dead during 6 months), recurred (alive with recurred acute left heart failure) and stable (alive without recurred acute left heart failure) groups. The prognostic value of serum NT-proBNP and CA125 levels alone and in combination were analysed. Results The serum CA125 levels were significantly different between different groups ( = 0.013), and the levels were significantly increased in recurred and dead groups compared with stable group ( =0.004 and 0.030, respectively). The mortality risk during 6 months after discharge was significantly higher in patients with positive CA125 and NT-proBNP compared with other patients. Conclusions The combination of CA125 and NT-proBNP levels could accurately predict the mortality risk in patients with acute heart failure during six months after discharge.关键词
急性心力衰竭/CA125/NT-proBNP/预后/死亡率Key words
acute heart failure/carbohydrate antigen-125/N-terminal pro-brain natriuretic peptide CA125/prognosis/mortality分类
医药卫生引用本文复制引用
汤子鸣,秦俭..急性心力衰竭患者联合检测血清糖类抗原CA125和N末端脑钠肽原的临床意义[J].中国现代医学杂志,2016,26(24):51-53,3.
