中国药理学通报2016,Vol.32Issue(12):1643-1647,5.DOI:10.3969/j.issn.1001-1978.2016.12.004
丹参酮类化合物研究进展
Research progress of Tanshinones
摘要
Abstract
Salvia miltiorrhiza bunge (Dan shen in Chinese)is extracted from dried roots and rhizomes of Labiatae Salvia.Tan-shinones are the main lipid-soluble components in Salvia,each has specific pharmacological activity.This review focuses on the research progress of Tanshinones on cardiovascular diseases,an-ti-inflammatory and immunomodulatory effects, anti-tumor effect,hepatocyte protection and neuroprotective effects.Thera-peutic effects and mechanisms of Tanshinones on diverse disea-ses are summarized,pharmacokinetics and pharmaceutic evalua-tion were concluded.This review provides a global understand-ing about Tanshinones as a class of effective and promising can-didates for further studies,and lays a foundation for developing new Tanshinone-based agents according to the characteristics of Tanshinones.关键词
丹参酮/临床应用/药理作用/药效机制/药代动力学/制剂评价Key words
Tanshinones/clinical appacation/pharmacologic effects/therapeutic mechanism/pharmacokinetics/pharmaceutic evaluation引用本文复制引用
刘慧颖,姜长涛,冯娟,王宪..丹参酮类化合物研究进展[J].中国药理学通报,2016,32(12):1643-1647,5.基金项目
国家优秀青年科学基金资助项目 ()