中国医学科学院学报2016，Vol.38Issue(6)：735-738,4.DOI:10.3881/j.issn.1000-503X.2016.06.019
库欣病患者认知障碍的研究进展
Advances in Evaluation of Cognitive Impairment in Patients with Cushing’ s Disease
摘要
Abstract
Cushing’ s disease ( CD) is a relatively rare disease, characterized by pathological hypercor-tisolism secondary to excessive adrenocorticotrophic hormone that is secreted by pituitary adrenocorticotrophic hor-mone adenoma or hyperplasia. In addition to the typical clinical symptoms such as moon face, buffalo hump, and central obesity, the CD patients may also experience mental disorders and cognitive dysfunction. This review mainly focuses on the cognitive state of CD patients, the mechanisms of cognitive impairment caused by high cor-tisol levels, and the imaging findings ( especially magnetic resonance imaging) for the evaluation of cognitive functions.关键词
库欣病/认知障碍/发病机制/磁共振成像Key words
Cushing’ s disease/cognitive impairment/pathogenesis/magnetic resonance imaging分类
医药卫生引用本文复制引用
毛伟玉,有慧,幸兵,朱惠娟,冯逢..库欣病患者认知障碍的研究进展[J].中国医学科学院学报,2016,38(6):735-738,4.基金项目
首都临床特色应用研究(Z151100004015099) Supported by the Capital Characteristic Clinical Application Research (Z151100004015099) （Z151100004015099）
