摘要
Abstract
Objective To analyze the influencing factor of insulin resistance and B-cell function in patients with type 2 diabetes mellitus (T2DM). Method The results of oral glucose tolerance test (OGTT) and insulin releasing test were statistically analyzed. The results were divide into groups by age, course, body mass index (BMI), glycosylated hemoglobin (HbA1c), nation and other factors, analyzed its relationship with BMI, HbA1c, insulin secretory volume, B-cell function, homeostasis model assessment of insulin resistance (HOMA-IR). Result HOMA-IR, insulin secretory volume and B-cells functiont gradually decreased with the progress of disease; insulin secretory volume, HOMA-IR, B-cells function increased gradually with the increase of BMI;insulin secretory volume and B-cells function with the increase of HbA1c gradually decreased; Uygur secretory volume and HOMA-IR was much higher; HOMA-IR was not related to age, course of disease, HbA1c (P >0.05), related to BMI (P < 0.01). B-cell functions was not related to age, course of disease (P > 0.05), related to HbA1c and BMI (P < 0.01). Conclusion Insulin resistance in T2DM is associated with BMI, B-cell function may be related to BMI, HbA1c and nation.关键词
2型糖尿病/胰岛B细胞/胰岛素抵抗Key words
Type 2 diabetes mellitus/B-cell/Insulin resistance
