中国药业2016，Vol.25Issue(24)：33-35,36,4.
脂肪乳用于急性有机磷农药中毒肺损伤临床评价
Fat Emulsion Used for Lung Injury of Acute Organophosphorus Pesticide Poisoning
摘要
Abstract
Objective To investigate the application value of fat emulsion supply for lung injury of acute organophosphorus pesticide poisoning. Methods 36 acute organophosphorus pesticide poisoning patients were randomly divided into two groups. 20 cases in the control group were treated with completely gastric lavage,penehyclidine hydrochloride,pralidoxime chloride,hemopurification and mechani-cal ventilation. 20% concentration of fat emulsion (250 mL per day) was provided 3 d among the other 16 cases in the treatment group on the basis of the control group treatment. Difference of the oxygenation index,success rate of rescue,cure and improvement rate and total hospital stay between two groups were observed. Results The 24 h oxygenation index and the cure and improvement rate in the treatment group was significantly higher than that in the control group;the percentage of mechanical ventilation application in the treatment group was lower than the control group among severe poisoning patients. However,the average hospital stay of control group was shorter than that of the treatment group( P ﹤ 0. 05)and the success rate of rescue between two groups did not show statistical differences ( P ﹥ 0. 05). Conclusion The therapy of fat emulsion supply in the acute organophosphorus pesticide poisoning could re-duce lung injury,reduce the application of mechanical ventilation in severe poisoning patients,increase the cure and improvement rate and has good clinical effect.关键词
脂肪乳/急性有机磷农药中毒/肺损伤Key words
fat emulsion/acute organophosphorus pesticide poisoning/lung injury分类
医药卫生引用本文复制引用
秦朴,蔡云刚,秦亚伟,张君国,余成艳,秦智红,杨波..脂肪乳用于急性有机磷农药中毒肺损伤临床评价[J].中国药业,2016,25(24):33-35,36,4.基金项目
重庆市卫生局科研项目，项目编号2013－2－276。 （）
