摘要
Abstract
Objective To investigate the curative effect of leuprorelin combined with Mirena in the treatment of adenomyosis after laparoscopic resection.Methods 104 patients with adenomyosis treated in our hospital from August 2014 to August 2015 were divided into observation group (n=52) and control group (n=52) according to the number of patients admitted to hospital by the random number table.The observation group was treated by leuprorelin combined with Mirena after laparoscopic resection while the control group was treated by the leuprorelin treatment. Two groups were followed up for 1 year to compare the menstrual volume PBAC score and dysmenorrhea VRS score before treatment,3 months,6 months,12 months after treatment,and record the adverse reactions of the two groups after treatment.ResultsThe PBAC scores in the observation group were respectively (41.15+6.61),(33.38+4.11),(23.62+2.93) points 3 months,6 months,12 months after treatment,which were statistically higher than those of the control group (t=6.172, 4.836, 4.365,P<0.05).The VAS scores in the observation group were respectively (1.32+0.24),(0.98+0.17),(0.46+0.15) points 3 months,6 months,12 months after treatment,which were statistically lower than those of the control group (t=3.985,4.012,4.996,P<0.05).The menopausal symptoms,irregular vaginal bleeding,pain,breast pain and other adverse reactions of two groups after treatment were not significant difference (χ2=0.078,0.102,0,0.343,0.443, P>0.05).ConclusionLeuprorelin combined with Mirena has better effect in the treatment of the adenomyosis after lesion resection compared treated by simply using leuprolide.关键词
子宫腺肌病/亮丙瑞林/曼月乐/痛经评分/月经量评分Key words
Adenomyosis/Leuprolide/Mirena/Dysmenorrhea score/Menstrual score分类
医药卫生
