摘要
Abstract
Objective To study the effect of chemiluminescence enzyme immunoassay and ELISA for the testing of hepatitis C antibody.Methods 332 cases of hepatitis C patients cured in our hospital from December 2014 to November 2015 were randomly divided into control group and observation group with 166 cases in each. The blood of patient was extracted, and the hepatitis C antibody of patient was detected. In the control group, the positive detection rate was detected by ELISA method, and the positive detection rate of the patients in the observation group was detected by the chemiluminescence enzyme immunoassay method.ResultsThe positive detection rate of hepatitis C antibody was 97.6%, which was significantly higher than that of ELISA method. The positive rate of hepatitis C antibody was 93.4%, and the difference was statistically significant (P<0.05). Furthermore, the CLEIA for anti AMA-M2 antibody positive rate was 78.3%, the positive rate was significantly higher than that of ELISA method with12.7%. Chemiluminescence enzyme immunoassay for anti 3E antibody positive rate was 72.9%, the positive rate was significantly higher than that of ELISA method with13.3%. Chemiluminescence enzyme immunoassay for anti SP100 antibody positive rate was 38%, which was higher than that of ELISA method with 14.5%. Chemiluminescence enzyme immunoassay for anti PML antibody positive rate was 56%, which was higher than that of ELISA 11.4%. Chemical analysis method for anti GP210 antibody positive rate was 48.2% luminescence enzyme immunoassay, the positive rate was significantly higher than that of ELISA with 6%.ConclusionThe CLEIA in hepatitis C antibody test is significantly better than that of ELISA method. It can be extended to hepatitis C antibody test.关键词
化学发光酶免疫法/ELISA/丙型肝炎抗体Key words
Chemiluminescence enzyme immunoassay/Enzyme linked immunosorbent assay/Hepatitis C antibody分类
医药卫生
