北京中医药大学学报2017，Vol.40Issue(1)：65-69,5.DOI:10.3969/j.issn.1006-2157.2017.01.013
阳虚体质者粪便的代谢组学研究
NMR-based metabonomics study on faeces of subjects with yang-deficien-cy constitution
摘要
Abstract
Objective To compare the endogenous metabolites in faece of subjects with yang-deficiency constitution and the subjects with balanced constitution (healthy persons).Methods Faece samples of 30 persons with yang-deficiency constitution and 30 healthy persons were collected and analyzed by using nuclear magnetic resonance(NMR)-based metabonomics method.And the specific metabolites of faeces of yang-deficiency constitution persons were measured using multivariate statistical analysis OSC-PLS. Results The content of butyrate,acetate,methionine,succinate,glucose in yang-deficiency constitution persons were lower than those in healthy persons,while the content of propionate,alanine,lactate were higher.Conclusion There were differences in metabolism of energy,amino acid and glucose between persons with yang-deficiency constitution and persons with balanced constitution,which should be related to the viscera function and the composition of gut microbiota.关键词
阳虚体质/核磁共振/代谢组学Key words
yang-deficiency constitution/nuclear magnetic resonance (NMR)/metabonomics分类
医药卫生引用本文复制引用
王均衡,李英帅,骆斌,岳子敬..阳虚体质者粪便的代谢组学研究[J].北京中医药大学学报,2017,40(1):65-69,5.基金项目
国家自然科学基金青年科学基金项目 （）
