高等学校化学学报2017，Vol.38Issue(1)：35-40,6.DOI:10.7503/cjcu20160654
酰胺类杨梅素衍生物的合成及抑菌活性
Synthesis and Antibacterial Activities of Myricetin Derivatives Containing Acidamide Moiety†
摘要
Abstract
Twelve novel myricetin derivatives containing acidamide moiety were designed and synthesized from myricetin. All the compounds were characterized by 1H NMR, 13C NMR and HRMS. The preliminary bioassay results indicated that all of the title compounds exhibited a certain antibacterial activities in vitro against X. oryzae, X. citri and R. solanacearum. Moreover, These title compounds 3a, 3e, 3f, 3h and 3k displayed good antibacterial activities against the above three plant pathogenic bacteria. Especially, compound 3e displayed 100% inhibition rates against X. oryzae and R. solanacearum at 200 μg/mL, respectively, which is more than the control bismerthiazol(72. 85% and 75. 86%, repectively).关键词
杨梅素衍生物/酰胺/抑菌活性Key words
Myricetin derivatives/Acidamide/Antibacterial activity分类
化学化工引用本文复制引用
肖维,阮祥辉,李琴,张菊平,钟新敏,谢艳,王晓斌,黄民国,薛伟..酰胺类杨梅素衍生物的合成及抑菌活性[J].高等学校化学学报,2017,38(1):35-40,6.基金项目
国家自然科学基金（批准号21462012）、贵州省优秀青年科技人才项目（批准号201535）和贵州大学研究生创新基金（批准号2016078）资助．? Supported by the National Natural Science Foundation of China（ No．21462012）， the Excellent Young Talents of Science and Technology in Guizhou Province， China（ No．201535） and the Innovation Fund for Graduate Student of Guizhou University， China（ No．2016078）． （）
