广东医学2016，Vol.37Issue(24)：3673-3677,5.
中老年高血压合并2型糖尿病患者糖化血红蛋白与血压变异性的相关性研究
The correlation of glycosylated hemoglobin and blood pressure variability in elderly patients with hypertension and type 2 diabetes mellitus
摘要
Abstract
Objective To investigate the correlation between glycosylated hemoglobin ( HbA1C ) and blood pres-sure variability (BPV) in elderly patients hypertension and type 2 diabetes mellitus (T2DM).Methods A total of 144 elderly patients with hypertension and T 2DM were included.HbA1C and BPV were measured and the correlation between them were analyzed.According to HbA1C level, all participants were divided into normal group (HbA1C <6.0%, n=97), high-normal group (6.0%≤HbA1C <7.0%, n=31) and risen group (HbA1C >7.0%, n=16).The BPV inde-xes correlated to the HbA 1C were analyzed and further compared among the three groups .Results In elderly patients with hypertension and T2DM, HbA1C level was significantly correlated with BPV indexes , including night mean SBP , CV of day SBP, ARV of day SBP, 24-hour SV of SBP and day SV of SBP .The night mean SBP, ARV of day SBP, 24-hour SV of SBP and day SV of SBP in risen group were significantly higher than those in normal group .Meanwhile , day ARV of SBP and day SV of SBP in risen group were significantly higher than those in normal -high group .Conclusion In elderly patients with hypertension and T 2DM, there is a significant correlation between HbA 1C and BPV, positive control of blood glucose level would benefit the BPV control , thereby reducing the target organ damage .关键词
中老年高血压/2型糖尿病/糖化血红蛋白/血压变异性Key words
elderly hypertension/type 2 diabetes mellitus/glycosylated hemoglobin/blood pressure variability引用本文复制引用
黄江明,徐琳,邱健,马骏..中老年高血压合并2型糖尿病患者糖化血红蛋白与血压变异性的相关性研究[J].广东医学,2016,37(24):3673-3677,5.基金项目
广东省科技计划项目重大科技专项基金项目（编号2013A022100036），广东省科技计划项目 （）
