国际妇产科学杂志2016,Vol.43Issue(6):681-685,5.
子宫内膜异位症相关卵巢癌病因研究进展
Advances in the Etiology of Endometriosis-associated Ovarian Cancer
摘要
Abstract
Endometriosis (EMs) is a benign lesions on pathology, but it has similar characteristics with malignant tumor such as infiltration, plant growth and damage the surrounding tissue, distant metastasis, and easy to relapse. Moreover, having a certain proportion of EMs histomorphology changes will happen, from atypical endometrial ectopic tissues further into cancer. Recently, EMs malignant transformation has received extensive attention of scholars from all over the world. Although the connection between EMs and ovarian cancer has been reported by scholars and has accepted diagnostic criteria, with the increase of the incidence of endometriosis and ovarian cancer, etiology, mechanisms and the epidemiological characteristics of endometriosis-associated ovarian cancer (EAOC) have become a research focus in recent years. This artical is to review the current data regarding the pathogenesis of EMs malignant transformation associated with gene mutation, apoptosis, inflammation, immunity, oxidative stress, estrogen.关键词
子宫内膜异位症/卵巢肿瘤/突变/子宫内膜异位症相关卵巢癌Key words
Endometriosis/Ovarian neoplasms/Mutation/Endometriosis-associated ovarian cancer引用本文复制引用
银琪,生秀杰..子宫内膜异位症相关卵巢癌病因研究进展[J].国际妇产科学杂志,2016,43(6):681-685,5.基金项目
广东省公益研究与能力建设项目 ()