临床与病理杂志2016，Vol.36Issue(12)：1917-1922,6.DOI:10.3978/j.issn.2095-6959.2016.12.005
活性氧联合玻璃酸钠治疗膝关节退行性骨关节炎的疗效观察
Observation on the therapeutic effect of reactive oxygen combined with sodium hyaluronate in the treatment of knee degenerative osteoarthritis
陈庆贤 1林红满 1陈海 1刘丽霞 1李巨元1
作者信息
- 1. 海南省儋州市第一人民医院药剂科，海南 儋州 571700
- 折叠
摘要
Abstract
Objective:To observe the effect of reactive oxygen combined with sodium hyaluronate in the treatment of knee degenerative osteoarthritis (DOA).Methods: 176 cases of patients with knee joint DOA in our hospital from June 2012 to June 2014 were selected. According to random number table for the qualiifed subjects prospective randomized clinical research, the patients were divided into observation group and control group, 88 cases for each. hTe control group were treated with sodium hyaluronate injection, and the observation group was treated with medical ozone injection. The therapeutic effect, joint function and adverse reactions of the two groups were compared.Results: hTe visual analogue scale (VAS) score of two groups of patients atfer treatment were signiifcantly lower, and increased gradually atfer 6 months of treatment, the observation group’s VAS score were signiifcantly lower than the control group (P<0.05) atfer treatment. 5 weeks atfer treatment, the Lequesne index and the tenderness of the knee joint of two groups decreased significantly, the activity of the joint increased signiifcantly, and the change of the observation group was more signiifcant (P<0.05). hTe clinical total effective rate in the observation group was 92%, which was signiifcantly higher than that in the control group (P<0.05). Conclusion: Reactive oxygen species combined with sodium hyaluronate can effectively improve pain situation and knee joint function of patients with knee DOA, which has good clinical effcacy, is safety and worthy of further promotion.关键词
活性氧/玻璃酸钠/膝关节/退行性骨关节炎/疗效Key words
reactive oxygen/sodium hyaluronate/knee degenerative osteoarthritis/curative effect引用本文复制引用
陈庆贤,林红满,陈海,刘丽霞,李巨元..活性氧联合玻璃酸钠治疗膝关节退行性骨关节炎的疗效观察[J].临床与病理杂志,2016,36(12):1917-1922,6.
