临床与病理杂志2016，Vol.36Issue(12)：2071-2075,5.DOI:10.3978/j.issn.2095-6959.2016.12.033
肺血管内皮细胞分泌功能的改变与急性肺损伤/急性呼吸窘迫综合征
Secreting function of pulmonary vessel endothelial cells with acute lung injury/acute respiratory distress syndrome
摘要
Abstract
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common clinical emergencies and severe disease. hTe mortality rate is as high as 25%—45%. hTe mainly treatment is limited to organ function and systemic supportive care treatment, especially respiratory support treatment, “waiting” to alleviate the lung injury. In the pathogenesis of ARDS, the pulmonary vascular endothelial cells (PVEC) are not only the mainly target cells to be damaged, but also the active inlfammatory cells and effector cells. And the degree of activation and damage of vascular endothelial cells (VEC) is closely related with the prognosis of ARDS. In this paper, we will focus on the changes of PVEC partial secretion function in the pathogenesis of ALI/ARDS.关键词
肺血管内皮细胞/急性肺损伤/急性呼吸窘迫综合征/分泌功能Key words
pulmonary vascular endothelial cells (PVEC)/acute lung injury/acute respiratory distress syndrome (ALI/ARDS)/secretion function引用本文复制引用
江秀芳(综述),陈泉,王德明(审校)..肺血管内皮细胞分泌功能的改变与急性肺损伤/急性呼吸窘迫综合征[J].临床与病理杂志,2016,36(12):2071-2075,5.基金项目
国家自然科学基金应急管理项目(81641152)；国家自然科学基金青年科学基金项目(81301625)；湖南省科学计划项目(2013FJ6006)。This work was supported by National Natural Science Foundation (81641152 and 81301625), and Hunan Provincial Science and Technology Department (2013FJ6006), P. R. China （81641152）
