化工进展2017,Vol.36Issue(1):305-315,11.DOI:10.16085/j.issn.1000-6613.2017.01.039
罗丹宁复合份菁染料在生物医学领域的研究进展
Biomedical research progress of rhodanine merocyanine dyes
摘要
Abstract
Rhodanine compound cyanine dye is a kind of widely used organic dyes that have high molar absorption coefficient,wide range of spectral response,and the high quantity of fluorescent rate. However,there are few reports on the direct applications in the field of biomedical dye types. This paper discussed the latest biomedical applications of rhodanine compound of cyanine dyes. Because of single component,well defined structure,and the stable properties,rhodanine compound cyanine dye has been applied to fight malaria,antitumor,photodynamic therapy,cell imaging,etc. It showed a certain activity in malaria and antitumor activity detection,and can be used as potential photosensitizer for light photodynamic therapy,andin vitro cell imaging. The rhodanine compound of cyanine dyes have good potential applications in biomedical field. The development of the novel structure and excellent performance of cyanine dyes will extend its application in the field of biomedical.关键词
罗丹宁复合份菁染料/抗疟疾/抗肿瘤/光动力疗法/细胞成像Key words
rhodanine cyanine dyes/malaria/antitumor/photodynamic therapy/cell image分类
化学化工引用本文复制引用
邓文婷,王兰英,关丽,张欢,哈超..罗丹宁复合份菁染料在生物医学领域的研究进展[J].化工进展,2017,36(1):305-315,11.基金项目
国家自然科学基金(21305109,81202492,81302706),陕西省科学技术厅自然科学基础研究计划(2014JQ2073,2014K02-11-01)及西安医学院博士启动基金(2012 Doc 09)项目。 ()