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罗丹宁复合份菁染料在生物医学领域的研究进展

邓文婷 王兰英 关丽 张欢 哈超

化工进展2017,Vol.36Issue(1):305-315,11.
化工进展2017,Vol.36Issue(1):305-315,11.DOI:10.16085/j.issn.1000-6613.2017.01.039

罗丹宁复合份菁染料在生物医学领域的研究进展

Biomedical research progress of rhodanine merocyanine dyes

邓文婷 1王兰英 2关丽 3张欢 3哈超1

作者信息

  • 1. 西安医学院药学院,陕西西安 710021
  • 2. 西北大学化学与材料科学学院,陕西西安 710127
  • 3. 西北大学化学与材料科学学院,陕西西安 710127
  • 折叠

摘要

Abstract

Rhodanine compound cyanine dye is a kind of widely used organic dyes that have high molar absorption coefficient,wide range of spectral response,and the high quantity of fluorescent rate. However,there are few reports on the direct applications in the field of biomedical dye types. This paper discussed the latest biomedical applications of rhodanine compound of cyanine dyes. Because of single component,well defined structure,and the stable properties,rhodanine compound cyanine dye has been applied to fight malaria,antitumor,photodynamic therapy,cell imaging,etc. It showed a certain activity in malaria and antitumor activity detection,and can be used as potential photosensitizer for light photodynamic therapy,andin vitro cell imaging. The rhodanine compound of cyanine dyes have good potential applications in biomedical field. The development of the novel structure and excellent performance of cyanine dyes will extend its application in the field of biomedical.

关键词

罗丹宁复合份菁染料/抗疟疾/抗肿瘤/光动力疗法/细胞成像

Key words

rhodanine cyanine dyes/malaria/antitumor/photodynamic therapy/cell image

分类

化学化工

引用本文复制引用

邓文婷,王兰英,关丽,张欢,哈超..罗丹宁复合份菁染料在生物医学领域的研究进展[J].化工进展,2017,36(1):305-315,11.

基金项目

国家自然科学基金(21305109,81202492,81302706),陕西省科学技术厅自然科学基础研究计划(2014JQ2073,2014K02-11-01)及西安医学院博士启动基金(2012 Doc 09)项目。 ()

化工进展

OA北大核心CSCDCSTPCD

1000-6613

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