化工进展2017，Vol.36Issue(1)：316-323,8.DOI:10.16085/j.issn.1000-6613.2017.01.040
β-甲基萘催化氧化合成维生素K3的研究进展
Research progress on the catalytic oxidation ofβ-methylnaphthalene to vitamin K3
摘要
Abstract
Vitamin K3 (VK3),an important intermediate for the synthesis of vitamin K,medicine and feed additive,can be obtained only by the artificial synthesis.β-methylnaphthalene (β-MN) can be directly oxidized to VK3 by green method but with many difficulties. Research on the catalytic oxidation of low-costβ-MN to VK3 by different oxidants,such as hydrogen peroxide,oxidizing salt and oxygen,is reviewed in this paper. The review is focus on the catalytic oxidation reactions using green oxidant, hydrogen peroxide. The latest research results on gas phase oxidation,electrolytic oxidation and microwave oxidation are mentioned. Due to the simple operation and low energy consumption, liquid-phase oxidation and gas phase oxidation should be the first choice for industrial production of VK3. Although the study on microwave oxidation is still at the early stage,the high-efficient and green microwave oxidation has drawn great attention. Finally,some suggestions for future synthesis of VK3, such as preparation of catalyst,selection of oxidants and solvents,are suggested.关键词
β-甲基萘/维生素K3/催化/氧化Key words
β- methylnaphthalene/vitamin K3/catalysis/oxidation分类
化学化工引用本文复制引用
张天永,刘晓思,李彬,朱少迪,杨玉秋..β-甲基萘催化氧化合成维生素K3的研究进展[J].化工进展,2017,36(1):316-323,8.基金项目
国家自然科学基金（21276187）、天津市自然科学基金（13JCQNJC05800）及天津市科技创新平台计划（14TXGCCX00017）项目。 （）
