基础医学与临床2017，Vol.37Issue(1)：118-122,5.
PI3K／Akt／mTOR信号通路及其相关基因突变与子宫内膜癌靶向性药物治疗的研究进展
Research advances of PI 3 K/Akt/mTOR signaling pathway with its related gene mutations and the targeted therapy for endometrial cancer
摘要
Abstract
Endometrial cancer ( EC) is one of the most common gynecological cancer ,of which the molecular biolog-ical mechanisms is very complex .In recent years, it has been reported that the abnormally regulated PI 3K/Akt/mTOR signaling pathway is significantly related with endometrial cancer .The mutation and abnormal activation of the receptors and kinase of the PI 3 K/Akt/mTOR signaling pathway is a potential therapeutic target of endometrial cancer .关键词
PI3K/Akt/mTOR信号通路/基因突变/子宫内膜癌/靶向治疗Key words
the PI3K/Akt/mTOR signaling pathway/gene mutations/endometrial cancer/targeted therapy分类
医药卫生引用本文复制引用
曹楚楚,黄炉仁,傅芬..PI3K／Akt／mTOR信号通路及其相关基因突变与子宫内膜癌靶向性药物治疗的研究进展[J].基础医学与临床,2017,37(1):118-122,5.基金项目
江西省科技计划 （）
