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超声热效应下海藻酸钠微球力学特性模型分析

赫培远 张建营 汲振余 张响 何美霞 徐洪亮 曹魏 邹敏 张丽果

军事医学2016,Vol.40Issue(12):937-940,4.
军事医学2016,Vol.40Issue(12):937-940,4.DOI:10.7644/j.issn.1674-9960.2016.12.001

超声热效应下海藻酸钠微球力学特性模型分析

Numerical model of shear module of alginate micro-beads under ultrasonic thermal effect

赫培远 1张建营 2汲振余 2张响 3何美霞 4徐洪亮 2曹魏 5邹敏 6张丽果2

作者信息

  • 1. 郑州大学生命科学学院,郑州 450001
  • 2. 河南省医药科学研究院,郑州 450052
  • 3. 郑州大学力学与工程科学学院,郑州 450001
  • 4. 郑州大学微纳成型技术国家级国际联合研究中心,郑州 450001
  • 5. 郑州大学第一附属医院神经内科,郑州450052
  • 6. 郑州大学附属郑州中心医院,郑州 450052
  • 折叠

摘要

Abstract

Objective To establish a numerical model of the shear module of alginate beads stimulated by ultrasonic sound.Methods The compression ratio and force of alginate beads were recorded with the compression test .The shear module of beads was measured with a Hertz model .When to alginate beads were stimulated ultrasonically for different durations , the ultrasonic stimulation power , ultrasonic pulse ratio , and changes in the shear module and solution temperature were measured.Results Temperatures in the solution and shear module of alginate beads increased under different ultrasonic stimulation conditions .Modeling analysis revealed the relationship between the shear module of alginate beads and the corresponding temperature .The shear module of beads was in a quadratic equation with temperature (20℃<T<80℃) .Residual analysis showed that the function had a good predictive and descriptive effect .Conculsion This function can be used as a good predictive model of the shear module of alginate beads at different temperatures .The results can facilitate the application of alginate beads to medical and biological research .

关键词

超声热效应/模型/海藻酸钠/剪切模量

Key words

ultrasonic thermal effect/modeling/sodium alginate/shear module

分类

通用工业技术

引用本文复制引用

赫培远,张建营,汲振余,张响,何美霞,徐洪亮,曹魏,邹敏,张丽果..超声热效应下海藻酸钠微球力学特性模型分析[J].军事医学,2016,40(12):937-940,4.

基金项目

国家自然科学基金青年基金资助项目(31600676);国家国际科技合作专项资助项目(2015DFA30550);河南省教育厅重点攻关资助项目(17A180036,17A180037);河南医学科技攻关资助项目 ()

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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