皮肤性病诊疗学杂志2016，Vol.23Issue(6)：367-371,375,6.DOI:10.3969/j.issn.1674-8468.2016.06.002
隆突性皮肤纤维肉瘤35例临床分析
Clinical Analysis on 35 Cases of Dermatofibrosarcoma Potuberans
孙凯亮 1陈辉 2李玉梅 3周春红 1万苗坚 4李华 3吴涛5
作者信息
- 1. 珠海市慢性病防治中心，广东 珠海 519070
- 2. 广州医科大学附属第三医院病理科，广东 广州510150
- 3. 珠海市第二人民医院病理科，广东 珠海 519000
- 4. 中山大学附属第三医院皮肤科，广东广州 510630
- 5. 广州市金域医学检验中心，广东 广州 510330
- 折叠
摘要
Abstract
Objective:To discuss the clinical characteristics , sonographic findings , surgical treatment and pathological diagnosis and differential diagnosis of dermatofibrosarcoma protuberans ( DFSP) .Methods:35 cases of DFSP were analyzed retrospectively .The clinical features , ultra-sonic features , histopathological features , treatment and prognosis were retrospectively analyzed . Results:There were 22 males and 13 females , the average age of the patients were ( 35.4 ± 12.4) years old.Typical clinical manifestation included skin patches , plaques or nodules, and without ulcer .The involved area in most patients is the trunk .Histopathological characteristics for the consistency of spindle tumor cells showed storiform or radial wheel-like arrangement , infiltra-tive growth, focal prominent atypic tumor cells , similar to changes in fiber sarcomatoid tumor . Tumor cells expressed vimentin .There were one case of recurrence in this group of patients with MMS after 1 year, and 2 cases after 3 years.Conclusion:DFSP has multiplex clinical manifesta-tions and was easily to be misdiagnosed .It can be further confirmed by tissue pathology and im-mune group examination .MMS is the first choice in its treatment .关键词
隆突性皮肤纤维肉瘤/临床表现/超声表现/MMS手术/病理特点Key words
Dermatofibrosarcoma protuberans/Clinical manifestation/Ultrasonography/MMS surgery/Pathological characteristics分类
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孙凯亮,陈辉,李玉梅,周春红,万苗坚,李华,吴涛..隆突性皮肤纤维肉瘤35例临床分析[J].皮肤性病诊疗学杂志,2016,23(6):367-371,375,6.
