药学研究2016，Vol.35Issue(12)：717-720,4.DOI:10.13506/j.cnki.jpr.2016.12.010
抗肿瘤多肽药物的作用机制及研究进展
Research progress and mechanism of anti-tumor peptides drugs
摘要
Abstract
Cancer is a kind of malignant disease which is a difficult problem in the world.At present,many clinical therapy and drugs are unable to avoid the drawbacks such as poor targeting,strong side effects and drug resistance.It is im-portant to look for anti-tumor drugs which are high effective,low toxic and easily available.Peptides stand out because of their features in many kinds of anti-tumor drugs,that depends on their small molecular weight,strong targeting,high activi-ty,low toxicity,easy to wear membrane and so on.Peptides have get extensive attention in the anti-tumor experimental study and clinical application.This paper classified anti-tumor peptides according to the mechanism and sources,respectively in-troduced apoptosis-promoting peptides,immunotherapied peptides,fusional peptides and other peptides,in the hope of pro-viding reference for screening,classifying and studying anti-tumor peptide.关键词
抗肿瘤/细胞凋亡/融合多肽/免疫治疗Key words
Anti-tumor/Cell apoptosis/Fusion peptides/Immunotherapy分类
医药卫生引用本文复制引用
王淑静,刘欢,赵建凯,任爽,孙薇薇,张文君,张家宁,张寒..抗肿瘤多肽药物的作用机制及研究进展[J].药学研究,2016,35(12):717-720,4.基金项目
研究生创新科研项目（No.YJSCX2015-394HSD）；哈尔滨市科技创新人才研究专项基金资助 （）
