实用肝脏病杂志2017，Vol.20Issue(1)：60-64,5.DOI:10.3969/j.issn.1672-5069.2017.01.016
155例酒精性肝病患者临床特征分析
Clinical features of patients with alcoholic liver disease:An analysis of 155 cases
摘要
Abstract
Objective To summarize the clinical characteristics of patients with alcoholic liver disease (ALD). Methods The clinical data of 155 patients with ALD were retrospectively analyzed from January 2014 to July 2015 in the Taizhou People's Hospital. Results Out of 155 cases,there were alcoholic fatty liver(AFL) in 24, alcoholic hepatitis (AH) in 83 and alcoholic cirrhosis (AC) in 48. The farmers and self-employed businessmen accounted for 34.8% and 21.9%,respectively;The average age was (55.5±12.2) yr old,middle-aged (45 to 59 yr old) were 44.5%;The average age of patients with AC was (63.1±12.3) yr old,significantly greater than (49.7±7.2) yr old in patients with AFL or (52.9±11.3) yr old in patients with AH (P<0.05);The average ethanol intake in patients with AC was(157.5±69.3) g/d,significantly higher than(105.7±50.6) g/d in patients with AFL or (125.3±66.4) g/d in patients with AH (P<0.05);The average drinking period in AC patients was (31.7±12.0) yrs,significantly longer than (22.6±6.7) yrs in patients with AFL or(22.9±10.1) yrs in patients with AH(P<0.05);Logistic analysis showed that the age,ethanol intake and drinking period were independent risk factors for alcoholic liver cirrhosis;serum elevated GGT levels was found in 69.0%,increased erythrocyte mean corpuscular volum (MCV) was in 38.1 % and ratio of AST/ALT>2 was in only 17.4%. Conclusions Patients with ALD were mainly in middle-aged men. Age,ethanol intake and drinking period are risk factors for liver cirrhosis in ALD patients. The ratio of AST/ALT,serum GGT levels and MCV are not good indicators for patients with ALD, and the diagnosis might be dependent on comprehensive clinical data.关键词
酒精性肝病/临床特点/危险因素/AST/ALT比值Key words
Alcoholic liver disease/Clinical characteristics/Risk factor/Ratio of AST/ALT引用本文复制引用
叶茂聪,李阳,肖丽,杨秀珍,耿爱文,沈美龙,咸建春,徐洪涛..155例酒精性肝病患者临床特征分析[J].实用肝脏病杂志,2017,20(1):60-64,5.基金项目
江苏省干部保健科研课题 （）
