天津中医药2017，Vol.34Issue(1)：69-72,4.DOI:10.11656/j.issn.1672-1519.2017.01.17
中药复方及有效成分对骨骼肌胰岛素抵抗PI3K/AKT通路的影响
Effect of Chinese medicine compound and active ingredient to insulin resistance of musculi skeleti by PI3K/AKT pathway
摘要
Abstract
Type 2 diabetes mellitus (T2DM) is a kind of metabolic disease caused by polygenic inheritance. The main pathophysiological characteristics of T2DM is insulin resistance (IR), and musculi skeleti is the main part of IR. The development mechanism of musculi skeleti insulin resistance correlates to PI3K/AKT signal pathways. Clinical and experimental research shows that Chinese medicine com-pound and active ingredient can control IR of musculi skeleti and help to prevent and treat T2DM. Therefor, this article discussed the im-provement of musculi skeleti IR with Chinese medicine compound and active ingredient by PI3K/AKT pathway.关键词
2型糖尿病/骨骼肌/胰岛素抵抗/中药Key words
type 2 diabetes mellitus/musculi skeleti/insulin resistance/Chinese medicine分类
医药卫生引用本文复制引用
张碧溦,田春雨,李继安,喇孝瑾,焦子珊,徐雪梅,林椠,王晨斌..中药复方及有效成分对骨骼肌胰岛素抵抗PI3K/AKT通路的影响[J].天津中医药,2017,34(1):69-72,4.基金项目
河北省国际科技合作计划项目（13392502D）；河北省自然科学基金资助项目（H2015209025）；河北省中医药管理局科研计划项目（2016070）；河北省高等学校科学技术研究项目（QN2015119）。 （）
