陕西科技大学学报（自然科学版）2017，Vol.35Issue(1)：120-123,138,5.
水蓼化学成分抑菌和抗氧化活性研究
Antibacterial and antioxidant activity of the chemical compositions of Polygonum hydropiper L.
摘要
Abstract
To study on the antibacterial activity of the 1 1 compounds isolated from Polygo-numhydropiper L.and some compounds′antioxidant activity was measured by microdilu-tion method on 9 6-well plates.The minimum inhibiting concentration (MIC)was used for e-valuating the degree of antibacterial ability of each compound.The antioxidant capacity was measured by the DPPH radical-scavenging rate.The curves were plotted and the IC50 of com-pounds was determined by using origin 70 software,with IC50 expressing antioxidant capacity of different compounds.The results showed that the 1 1 compounds from Polygonum hy-dropiper L.manifested different degree of antibacterial activity,and the flavonoids had good antibacterial effect,quercetin showed the best activity to restrain the growth of the Staphy-lococcus aureus with MIC value of 3 1 .3μg · mL-1 .The compounds detected showed good antioxidant activity,and the antioxidant effect of quercetin,gallic acid and ellagic acid are better than vitamin C.Results indicate that these compounds isolated from Polygonum hy-dropiper L.have good antibacterial and antioxidant activity.The different activity of fla-vonoids is because of their different structures.The more enol structure in the flavonoids,the stronger antioxidant capacity it has.关键词
水蓼/化学成分/抑菌活性/抗氧化活性/构效关系Key words
Polygonumhydropiper L./chemical compounds/antibacterial activity/antioxi-dant activity/QSAR分类
药学引用本文复制引用
马养民,李梦云,郭林新,乔珂,范超..水蓼化学成分抑菌和抗氧化活性研究[J].陕西科技大学学报（自然科学版）,2017,35(1):120-123,138,5.基金项目
国家公益性行业（林业）科研专项项目 （）
