中国美容医学2016，Vol.25Issue(12)：49-53,5.
防脱复合中药单体自微乳及微乳凝胶剂的研究
Research of self-microemulsion and microemulsion gel of anti-hair loss compound Chinese medicine monomer
摘要
Abstract
Objective To study self-microemulsion and microemulsion gel of anti-hair loss compound Chinese medicine monomer, at the same time, its physical, chemical and stability performance are studied. Methods Screened suitable oil phase, surfactant and cosurfactant, and water titration method was used to draw the ternary phase diagram, Screened the best of Km, also investigated the average particle size and stability of it. Results When Km is 2, and the suitable prescription is PEG-40 hydrogenated castor oil: glycerol: octyldodecanol: compound Chinese medicine monomer (52:26:12:10),the average particle size of self-microemulsion is 22.64 nm and it is stable in low and normal temperature, similarly, the average particle size of microemulsion gel is 42.87 nm and it is stable in tree different condition including heat resistant, hardy and normal temperature. Conclusion Self-microemulsion and microemulsion gel of anti-hair loss compound Chinese medicine monomer is a transdermal drug delivery system that have application prospect for simple of preparation technology, small size, good stability.关键词
自微乳/微乳凝胶剂/复合中药单体/经皮给药制剂/最佳KmKey words
self-microemulsion/microemulsiongel/compound Chinese medicine monomer/transdermal drug delivery system/the optimum Km分类
医药卫生引用本文复制引用
刘彩云,王卓娅,罗欣茹,章戴荣,梁高卫,吴培诚..防脱复合中药单体自微乳及微乳凝胶剂的研究[J].中国美容医学,2016,25(12):49-53,5.基金项目
广东省科技特派员工作站资助项目(2014A090906013) （2014A090906013）
