中国药房2017，Vol.28Issue(1)：61-63,3.DOI:10.6039/j.issn.1001-0408.2017.01.16
正交试验优化余甘子配方颗粒的提取工艺研究
Study on Optimization of the Extraction Technology for Phyllanthus emblica Formula Granule by Orthogo-nal Test
摘要
Abstract
OBJECTIVE:To optimize the extraction technology for Phyllanthus emblica formula granules. METHODS:Using the comprehensive evaluation result of the content of gallic acid and paste rate as index,water amount,extraction times,extracting time as factors,orthogonal test was designed to optimize the extraction conditions of P. emblica formula granules. Validation test was conducted. RESULTS:The optimal extraction technology of P. emblica formula granule was as follows as 12-fold water,ex-tracting for 2 times,1 hour each time. The validation results showed that the average paste rate was 30.44%(RSD=2.07%,n=3),and the average content of gallic acid was 8.12%(RSD=0.86%,n=3). CONCLUSIONS:The optimized extraction technolo-gy is stable and can provide the basis for standardized production technology of P. emblica formula granule.关键词
余甘子/配方颗粒/正交试验/提取工艺Key words
Phyllanthus emblica/Formula granules/Orthogonal test/Extraction process分类
医药卫生引用本文复制引用
魏彩彩,李雪利,郝磊,冯玉康,张风林,霍保军,李军山,陈钟..正交试验优化余甘子配方颗粒的提取工艺研究[J].中国药房,2017,28(1):61-63,3.基金项目
国家中医药管理局中医药科学技术研究专项课题(No.国中医药科2013ZX07) （No.国中医药科2013ZX07）
河北省科技计划项目(No.14272504D) （No.14272504D）
