中国医院用药评价与分析2016，Vol.16Issue(12)：1608-1609,1610,3.DOI:10.14009/j.issn.1672-2124.2016.12.008
不同水化疗程对急诊经皮冠状动脉介入术后对比剂肾病预防效果的对比观察Δ
Comparative Observation on Preventive Effects of Different Hydration Therapy on Contrast-induced Nephropathy After Emergency Percutaneous Coronary InterventionΔ
摘要
Abstract
OBJECTIVE:To compare and observe the preventive effects of different hydration therapy on contrast-induced nephropathy(CIN) after emergency percutaneous coronary intervention (PCI).METHODS:Retrospective analysis was conducted on data of 123 cases with emergency PCI aditted into the First Hospital of Danjiangkou Hospital from Mar . 2015 to Jun.2016 , according to different hydration therapy , patients were divided into three groups , with 41 cases in each. Before PCI, all patients were treated with intravenous 0.9%sodium chloride injection, with dripping speed of 1 ml/(kg・h) [patients with left ventricular ejection fraction lower than 30%, the dripping speed was 0.5 ml/(kg・h)].After surgery, continuous hydration was conducted on group A , B and C for 6 h, 12 h and 24 h.The incidence of CIN, serum creatinine (Scr), blood urea nitrogen(BUN), creatinine clearance rate (Ccr) and glomerular filtration rate (GFR) of three groups were compared.RESULTS:After surgery of 48h, the incidence of CIN in group C was 2.44%(1/41), significantly lower than that of group A[24.39%(10/41)] and group B[14.63%(6/41)], with statistically significant difference (P<0.05).The Scr, BUN, Ccr, GFR of group C were significantly better than those of group A and group B , with statistically significant difference(P<0.05).CONCLUSIONS:Patients after emergency PCI with 24 h hydration therapy can effectively protect patients’ renal function and prevent the CIN .关键词
水化疗法/经皮冠状动脉介入/对比剂肾病/预防效果Key words
Hydration therapy/Percutaneous coronary intervention/Contrast-induced nephropathy/Preventive effects分类
医药卫生引用本文复制引用
习华,张明玺..不同水化疗程对急诊经皮冠状动脉介入术后对比剂肾病预防效果的对比观察Δ[J].中国医院用药评价与分析,2016,16(12):1608-1609,1610,3.基金项目
2016十堰市科学技术研究项目 （）
