中国医院用药评价与分析2016，Vol.16Issue(12)：1626-1627,1628,3.DOI:10.14009/j.issn.1672-2124.2016.12.015
重组牛碱性成纤维细胞生长因子滴眼液联合玻璃酸钠滴眼液治疗干眼病的疗效观察
Observation on Efficacy of Recombinant Bovine Basic Fibroblast Growth Factor Combined with Sodium Hyaluronate Eye Drops in Treatment of Xerophthalmia
匡慧敏 1张汉滨1
作者信息
- 1. 汉川市人民医院眼科，湖北汉川 431600
- 折叠
摘要
Abstract
OBJECTIVE:To probe into the clinical efficacy of recombinant bovine basic fibroblast growth factor combined with sodium hyaluronate eye drops in treatment of xerophthalmia .METHODS: 90 patients xerophthalmia admitted into Hanchuan Prople’s Hospital from Feb.2014 to Nov.2015 were selected to be divided into observation group and control group via the number grouping method, with 45 cases in each.The control group were treated with sodium hyaluronate eye drops, while the observation group additionally received recombinant bovine basic fibroblast growth factor eye drops based on the control group.RESULTS:The total effective rate of observation group was 95.56%(43/45), significantly higher than that of control group 82.22%(37/45) , with statistically significant difference ( P<0.05) .After treatment , the tear breakup time of observation group was significantly higher than that of control group , yet SAI and SRI indicators were significantly lower than those of control group, with statistically significant difference (P <0.05).CONCLUSIONS: The efficacy of recombinant bovine basic fibroblast growth factor combined with sodium hyaluronate eye drops in treatment of xerophthalmia is remarkable with few adverse drug reactions and high safety .关键词
重组牛碱性成纤维细胞生长因子滴眼液/干眼病/临床疗效Key words
Recombinant bovine basic fibroblast growth factor eye drops/Xerophthalmia/Clinical efficacy分类
医药卫生引用本文复制引用
匡慧敏,张汉滨..重组牛碱性成纤维细胞生长因子滴眼液联合玻璃酸钠滴眼液治疗干眼病的疗效观察[J].中国医院用药评价与分析,2016,16(12):1626-1627,1628,3.
