中华耳科学杂志2016,Vol.14Issue(6):783-787,5.DOI:10.3969/j.issn.1672-2922.2016.06.016
LVAS患者3D-FLAIR影像表现及其临床意义
3D-FLAIR MRI Findings and Its Clinical significance in Patients with Large Vestibular Aqueduct Syndrome
刘颖 1曹代荣 1方哲明 1顾晰 2邢振1
作者信息
- 1. 福建医科大学附属第一医院影像科
- 2. 福建医科大学附属第一医院耳鼻咽喉头颈外科
- 折叠
摘要
Abstract
Subject To study characteristics of inner ears imaging with 3D-fluid-attenuated inversion recovery (3D-FLAIR) and its clinical significance in patients with large vestibular aqueduct syndrome (LVAS). Methods Study sub-jects included 30 patients (60 ears) with bilateral LVAS confirmed by water imaging with 3D-TSE sequence and 10 normal volunteers (20 ears). 3D-FLAIR sequence was performed using a 3-Tesla MR scanner. With comparison to labyrinth mor-phology on routine inner ear water imaging, characteristics of labyrinth signals were examined. Signal intensities (SI) in the endolymphatic sac, vestibule and cochlea was measured, and their correlation to the degree of hearing loss and patient age analyzed. Correlation between the SI ratio (SIRs) of the endolymphatic sac and patient age (degree of hearing loss) was in-vestigated. Results On 3D-FLAIR, high signal was present in 52 cochleae and 50 vestibules among the 60 ears with LVAS, and in none of the 20 normal ears. There was no significant difference between endolymphatic sac SI and that of the vesti-bule (t=-1.807,P=0.074) or cochlea (t=-1.2,P=0.233). There was no correlation between high SI in inner ear and hearing loss (P=0.840). A positive linear correlation, however, was found between SIR and patient age (r=0.510,P=0.000), but not between SIR and hearing loss (r=0.027,P=0.852). Conclusion Signal variation in inner ear seen on 3D-FLAIR se-quences does not correlate with the degree of hearing loss, but with patient age in LVAS.关键词
水抑制成像/大前庭导水管综合征/磁共振成像Key words
Fluid Attenuated Inversion Recovery/Enlarged Vestibular Aqueduct Syndrome/Magnetic Resonance Im-aging分类
医药卫生引用本文复制引用
刘颖,曹代荣,方哲明,顾晰,邢振..LVAS患者3D-FLAIR影像表现及其临床意义[J].中华耳科学杂志,2016,14(6):783-787,5.