中华耳科学杂志2016，Vol.14Issue(6)：819-822,4.DOI:10.3969/j.issn.1672-2922.2016.06.022
动物前庭功能的评价方法
Methods of vestibular function evaluation in animals
摘要
Abstract
Vestibular nervous system dysfunction can cause spatial orientation and balance disorders in both people and animals. The vestibule is an important part of the inner ear, with the same origin as but earlier development than the co-chlea, essentially matured at birth in mammals [1-3]. With a variety of animal models of vestibular dysfunction being devel-oped (pica rat model of motion sickness, vomiting mink model, etc.), understanding of the structure and function of the ves-tibular system has been continuously deepened. A systematic vestibular function evaluation system is not only important in basic research in animal models, but also helpful in diagnosis and treatment of vestibular diseases in the clinic. A number of vestibular evaluation methods exist, including caloric test to evaluate semicircular canal functions, cVEMP to evaluate saccu-lar function and oVEMP to evaluate utricular function. Studies in human subjects are limited by ethical constrains, and ani-mal studies are needed to advance understanding of vestibular structures and function and to improve diagnosis and treat-ment of vestibular disorders [4]. Experimental animals, however, are unable to cooperate during vestibular function examina-tion, the approach, therefore, must be different in animals than in people. This review focuses on several approaches for ves-tibular examination in animals.关键词
实验动物/前庭功能检测/前庭功能障碍Key words
experimental animals/vestibular function test/vestibular dysfunction分类
医药卫生引用本文复制引用
李亚,乔月华,杨仕明..动物前庭功能的评价方法[J].中华耳科学杂志,2016,14(6):819-822,4.基金项目
国家973计划重大科学研究计划干细胞项目（2012CB967900）；国家973计划重大科学问题导向项目（2011CBA01000) （）
国家自然科学基金青年项目（81400472）This work was supported by grants from the National Basic Research Program of China (973 Program)(#2012CB967900；2011CBA01000)，National Natural Science Foundation of China (81400472) （973 Program）
