重庆医学2017，Vol.46Issue(1)：48-50,3.DOI:10.3969/j.issn.1671-8348.2017.01.009
骨代谢生化指标与绝经后骨质疏松性腰椎骨折相关性分析
Study of correlation between biochemical markers of bone metabolism and postmenopausal osteoporotic vertebral fractures
摘要
Abstract
Objective To study correlation between biochemical markers of bone metabolism and postmenopausal osteoporot-ic vertebral fractures.Methods The clinical data of 100 cases with postmenopausal osteoporotic were study retrospectively.Fifty patients were postmenopausal osteoporotic,the rests were postmenopausal osteoporotic vertebral fractures.Lumbar spine,hip BMD,serum P1NP,β-CTX,N-MID,25-(OH)VitD and Ca2 + were recorded.Results There was a significant difference among ser-um P1NP,β-CTX and 25-(OH)VitD(P <0.05 ).There was positive correlation between postmenopausal osteoporotic vertebral fracture with serum P1NP (P <0.05),and negative correlation with serum 25-(OH)VitD (P <0.05),but had no correlation with serumβ-CTX (P >0.05).Conclusion Serum P1NP and 25-(OH)VitD could predict risk of postmenopausal osteoporotic vertebral fractures.Biochemical markers of bone metabolism combined with BMD could reduce postmenopausal osteoporosis fractures.关键词
骨质疏松,绝经后/绝经后期/骨密度/骨和骨组织/骨代谢生化指标/腰椎骨折Key words
osteoporosis,postmenopausal/postmenopause/bone density/bone and bones/postmenopausal osteoporotic/ver-tebral fractures分类
医药卫生引用本文复制引用
霍少川,董路珏,唐宏宇,刘勇,郭海,陈建发,邓章荣,陈德龙,王海彬..骨代谢生化指标与绝经后骨质疏松性腰椎骨折相关性分析[J].重庆医学,2017,46(1):48-50,3.基金项目
国家自然科学基金资助项目（81373655）；广东省省级科技计划项目（2013B021800226）。 （）
