重庆医学2017，Vol.46Issue(1)：51-53,3.DOI:10.3969/j.issn.1671-8348.2017.01.010
125 I粒子植入联合动脉灌注化疗治疗晚期胸腺癌的近期疗效评价
Short-term assessment of 1 2 5 I seed implantation combined with arterial infusion chemotherapy in treatment of advanced thymic carcinoma
摘要
Abstract
Objective To investigate the short term effect of 125 I seed implantation combined with arterial infusion chemo-therapy in the treatment of advanced thymic carcinoma.Methods Thirty-five cases of stage Ⅲ-Ⅳ thymic carcinoma confirmed by cytopathology were selected and divided into two groups according to different treatment means.The group A(18 cases)adopted 125 I seed implantation combined with arterial infusion chemotherapy (NP regimen).The group B(17 cases)were treated by arterial infusion chemotherapy (NP regimen).Results The remission rates(RR)in two groups were 66.7% and 47.1% respectively,and the disease control rates(DCR)were 83.3% and 64.7% respectively,the differences between the two groups were statistically sig-nificant(P<0.05).The increment values of quality of life(QOL)scores after treatment in the group A and B were 12.22±4.67 and 6.12 ±1.17 respectively,the difference between them was statistically significant (P<0.05).The increasing rates of the Karnofsky functional status score (KPS)after treatment in the group A and B were 66.7% and 41.2% respectively,the difference between them was statistically significant (P<0.05).Conclusion 125 I seed implantation combined with arterial infusion chemother-apy in the treatment of advanced thymic carcinoma has a remarkable short term effect and can significantly increases the patients′life quality.关键词
碘放射性同位素/输注,动脉内/胸腺肿瘤/手术后期间/125 I粒子植入/动脉灌注化疗Key words
iodine radioisotopes/infusions,intra-arterial/thymus neoplasms/postoperative period/125 I seed implantation/ar-terial infusion chemotherapy分类
医药卫生引用本文复制引用
王宇鹏,宁莉莉,屈波,韩玲,胡永进,许建辉,杜学明..125 I粒子植入联合动脉灌注化疗治疗晚期胸腺癌的近期疗效评价[J].重庆医学,2017,46(1):51-53,3.基金项目
国家自然科学基金面上项目（81272547）；武警后勤学院附属医院种子基金项目（FYM201609）。 （）
